Endocrine Abstracts

Immunoglobulin G4-related disease (IgG4-RD) is now a widely recognised multi-organ system disease characterised by elevated serum and tissue concentrations of IgG4. Two forms of thyroid involvement in IgG4-RD have been described, including Reidel’s thyroiditis (IgG4-related thyroid disease) and the fibrous variant of Hashimoto’s thyroiditis.Objective: To describe a case of the development of massive neck fibrosis and mediastinal fibrosis in a p...

Exposure to ionising radiation, changing levels of iodine nutrition, and increased pathologic diagnosis of clinically unimportant thyroid neoplasm have all been proposed as explanations for a world-wide rise in the incidence of thyroid carcinoma over the past 6 decades. Yakutia is geographically an area of endemic iodine deficiency (the population is about 1 million). According to previous research in the endemic areas there are more occasions of follicular thyroid cancer, whe...